While replicating an organizational sales process in the ERP-CRM environment, BMI is often preferred to have the quoting part of it and some level of price execution. The important decision revolves around having multiple commerce (quoting) processes or single for an organization. This decision definitely needs in-depth study of the company structure and considering the industry best practices to organize it. Leveraging this on technical feasibilities might lead to inefficiency.
Considering the BMI best practices, I was able to derive the basic parameters that are needed for evaluating this need.
The important parameters that need to be considered as Complexity of the Business Process, Localization Scope, User Experience and Administrative capabilities.
Business Process Complexity – If there are large differences between the Channel Sales and Internal Sales process & If there are large differences in the way the Pricing is handled within/per business process, then it makes sense to have multiple commerce processes within the organization.
Localization – A single commerce process can multi-currency or multiple languages. Pricing or related scripts in BML can easily handle multi-currency if designed efficiently. Hence for this case, a single commerce process is good enough.
User Experience – Since BMI is good at hiding and showing things based on conditions and not good at organizing elements within the quoting screen, if it a critical requirement to have dynamics on the quoting screen dynamically, it is recommended to have multiple processes, otherwise just one.
These are the basic elements which can help us evaluate the necessity of multiple commerce processes while designing the BMI architecture for an organization.
Srikanth Says 
would having multiple commerce process help or is supported by bmi for linking them individually with there own set of configurators? One-to-One mapping with config and commerce process? or…one-to-many with the same?
Multiple Commerce processes are needed to accommodate multiple business processes or multiple layers (which are completely discrete) with in a business. Configurators can be any, they can be mapped to one process also.